Aims/Introduction: Peroxisome proliferator activated receptor gamma (PPARG) is a nuclear hormone receptor of the ligand-dependent transcription factor involved in adipogenesis, and a molecular target of the insulin sensitizer, thiazolidinediones. The present study aimed to investigate whether the PPARG gene is associated with type 2 diabetes mellitus and its related traits within the population…
Aims/Introduction: The goal of the present study was to evaluate predictive factors for good efficacy and durability to sitagliptin with ongoing metformin or metformin plus glimepiride therapy in a real practice situation. The present observational study was carried out over a 60-week period and involved Korean patients with type 2 diabetes mellitus. Materials and Methods: A total of 100 mg of …
Aims/Introduction: Chronic hyperlipidemia impairs pancreatic b-cell function, referred to as lipotoxicity. We have reported an important role of endogenous reactive oxygen species (ROS) overproduction by activation of Src, a non-receptor tyrosine kinase, in impaired glucose-induced insulin secretion (GIIS) from diabetic rat islets. In the present study, we investigated the role of ROS productio…
Purpose: To analyze the effect of cultural factors on the subjective burden of primary home caregivers of older relatives. Design: Cross-sectional study. Primary home caregivers (N = 208) of older relatives were recruited in Spain using systematic random sampling. Methods: The data were collected in 2010 through interviews. The measures included sociodemographic characteristics, stressors (th…
Purpose: Exploratory studies establishing how well nurses have integrated genomics into practice have demonstrated there remains opportunity for education. However, little is known about educational gaps in multi-ethnic minority nurse populations. The purpose of this study was to determine minority nurses’ beliefs, practices, and competency in integrating genetics-genomics information into pr…
Purpose: The purpose of this study was to explore postpartum women’s sleep quality and its predictors in Taiwan. Design: Cross-sectional design. Methods: Postpartum women (N = 327) were recruited during their postnatal check-ups in Taiwan. Data were collected from October 2008 to July 2009 using a demographic form, the Pittsburgh Sleep Quality Index (PSQI), Physical Symptoms Checklist, Perc…
Purpose: This article provides an overview of the implications for patients’ health status and care needs when assessments are performed by nurses not licensed or competent to perform this task. The WaterlowTM scale (Judy Waterlow, The Nook, Stroke Road, Henlade, TAUNTON, TA3 5LX) scenario is used as a practice example to illustrate this case. Organizational Construct: The international nur…